Abstract: The climatic fluctuation of Altai Mts. during the Quaternary is indicated by investigation of stratigraphy, geomorphy and paleo glacier, which we reserched many localities in gold-places area. The studies also discovered the relationship between the climatic change and strata containing gold. We believe that Early Pleistocene Epoch is cold and moist, and then developed three glaciation, the second glaciation is strongest. Its interglacial period is the warmest and the most effective precipitation in Quaternary. The warmer and more effective precipitation periods are general identical with the gold-placers mineralized periods. According to the favourable climatic periods, chief gold-placers mineralized period are Early Pleistocene Epoch, the great interglacial period in Middle Pleistocene Epoch and late Pleistocene Epoch.