Abstract: Miqnin Basin is located in Gansu Province，northwest China where has the sharpest conflict of using water. Its total area is 5.2×103?km2,but the area of the oasis is just 1.5×103?km2 and is gradually reduced due to the shortage of water resources. Along with the population growth and the economic development,，groundwater in Minqin basin is excessively pumped, thus the groundwater depth is growing larger with the increasing span of time. In this paper，according to the data of monthly groundwater level from 1999 to 2008 provided by Minqin monitoring network，using the function of geo-statistical spatial analysis which is the part of Geographic Information System technique，the spatio-temporal patterns and spatial heterogeneity of groundwater depth is analyzed in recent 10?a. The interpolation results shows that the groundwater depth in Minqin Basin is growing larger yearly from 1999 to 2008. And the four funnel of groundwater depressions had appeared in 1999 and was gradually expanded and finally formed two biggest funnel of groundwater depressions when merging with nearby funnel in 2008. One-dimensional linear regression model has been established，and the results shows that the groundwater depth increases 0.52 meter every year. The values of C0/（C0+C）（Nugget/Sill） are far less than 25% in 10?a and this means the groundwater depth in Minqin Basin has a highly spatial relativity. The value of Sill increases every year which means that the Spatial heterogeneity of groundwater depth is increasing and the influence of human activities on groundwater has gradually became structural rather than random and will leading to the augmentation of the connectivity and frangibility of groundwater in Minqin Basin . The chief reason of this phenomenon is that the groundwater over-pumped every year. So in areas where groundwater has already been overdrawn，effective measures shall be taken，such as to readjust  the crop structure and enlarge the proportion of low water consumptive crops to protect groundwater resources in Minqin Basin.

Key words: Minqin Basin, spatio-temporal patterns of groundwater, spatial heterogeneity