发改委《十四五现代流通体系建设规划》强调“完善区域物流服务网络”，国务院《中国（新疆）自由贸易试验区总体方案》提出“建设联通欧亚的综合物流枢纽”。因此，研究新疆物流企业空间布局对完善区域物流服务网络和建设新疆自贸试验区具有重要战略意义。基于1992—2022年新疆物流企业的地理坐标数据，分析物流企业空间分布在不同尺度下的演变特征后，深入研究县域和网格尺度下物流企业空间布局形成机制与影响因素的空间异质性。结果表明：（1） 新疆物流企业呈现集聚发展状态，整体上发展成“单轴、单主核、多副核”的空间格局，局部上发展成“一主核、多副核”的空间格局。（2） 县域尺度下，新疆物流企业空间分布的热点区和次热点区始终分布在北疆地区，没有突破天山北坡的地理约束，但在较小的网格尺度下，次热点区最终突破天山北坡的地理约束。（3） 电商园区、综合保税区和人口密度是不同尺度下影响物流企业空间布局的重要因素，自然环境因素会与其他影响因素产生非线性增强的交互作用，需给予重视。（4） 新疆应重视物流园区建设、完善口岸功能性建设与经济发展，针对电商、工业园区、口岸、综合保税区等局部影响因素，因地制宜制定物流规划。研究深化了企业区位理论，为新疆欧亚物流枢纽及丝绸之路经济带核心区提供了理论支撑与实践指导。

The National Development and Reform Commission’s “14th Five-Year Plan for the Construction of a Modern Circulation System” emphasizes “improving the regional logistics service network”, while the State Council’s “Overall Plan for the China (Xinjiang) Pilot Free Trade Zone” proposes “building a comprehensive logistics hub connecting Europe and Asia”. Therefore, studying the spatial layout of Xinjiang logistics enterprises is of great strategic significance to improving the regional logistics service network and building the Xinjiang Pilot Free Trade Zone. Using the geographic coordinate data of Xinjiang logistics enterprises from 1992 to 2022, this study examines the geographical spatial distribution across different scales. This study explores the spatial heterogeneity of formation mechanisms and influencing factors at county and grid levels. The results indicate that: (1) Xinjiang logistics enterprises exhibit agglomeration, forming an overall spatial pattern of a “single axis, single main core, and multiple sub-cores”, while locally developing into a primary core with multiple sub-cores.(2) At the county level, logistics enterprise hotspots and sub-hotspots remain concentrated in northern Xinjiang, constrained by the northern slope of the Tianshan Mountains. However, at a finer grid scale, the sub-hotspots eventually expand beyond this geographical barrier. (3) E-commerce parks, comprehensive bonded zones, and population density significantly influence the spatial layout of logistics enterprises across different scales. Additionally, natural environmental factors can interact nonlinearly and should not be overlooked. (4) Xinjiang should prioritize logistics park development, enhance port functionality, and drive economic growth. In response to local influencing factors, such as e-commerce, industrial parks, ports, and comprehensive bonded zones, logistics plans should be expressed based on local conditions. The research deepened the enterprise location theory and provided theoretical support and practical guidance for the construction of Xinjiang’s Eurasian logistics hub and the core area of the Silk Road Economic Belt.